Project name: Project category: Kind of research: Country: Principle investigator:

The F508del-CFTR SRC

CFTR
Genetics
Basic research United Kingdom Dr. David Sheppard
Status: Ongoing
Abstract:

1) gain an understanding of when and where CFTR acquires its functional configuration;
2) detailed investigation of the consequences of f508del mutations;
3) investigate the CFTR structure required for exit from the endoplasmic reticulum and plasma membrane;
4) determine small molecules that regulate CFTR folding and potentially repair functionality

UK CF Trust Grant Code: Strategic Research Centre 005

Institute: University of Bristol
City: Bristol (England)
Project amount (€): 854.923,62

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