Project name: Project category: Kind of research: Country: Principle investigator:

Studying similarities and differences between mini-guts, mini-lungs and mini-noses

CFTR
Cell Biology
Basic research Netherlands Prof. Jeffrey Beekman
Start date: 2017
End date: 2021
Status: Ongoing
Abstract:

CFTR occurs in the upper and lower respiratory tract and also in mucous membranes in the intestine. The effects of CFTR mutations and drugs can be different between these different tissues. In this project we study CFTR and the effects of medication in different tissues of the same person. In the laboratory miniature small arms are grown from intestinal tissue, and properties in the mini-arms are compared with airway tissue from the lungs and the nose that is grown in the lab. In addition, new ways of studying CFTR function are being developed using airway tissues.

Website URL: https://www.ncfs.nl/onderzoek/lopend/hitcf
Researcher: Dr. Gimano Amatngalim
Institute: UMC Utrecht
City: Utrecht
Project amount (€): 25.000

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