Projects
To find and view projects use the search options.
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
CRISPR Knock-out of Class 1 CF Splicing Mutations |
New Therapies Genetics |
Basic research | Republic of Ireland | Dr. Patrick Harrison |
| Status: | Ongoing |
| Institute: | University of Cork |
| City: | Cork (Republic of Ireland) |
| Project amount (€): | 52.440 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Exploratory studies to investigate the effect of RPL554 in primary airway cells |
Genetics Cell Biology |
Basic research | United Kingdom | Dr. Katherine Banner |
| Status: | Ongoing |
| Institute: | University of Cardiff |
| City: | Cardiff (Wales) |
| Project amount (€): | 74.100 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
An application to fund the UK CF Gene Therapy Consortium core costs |
New Therapies Genetics |
Basic research | United Kingdom | Dr. Uta Griesenbach - Dr. Deborah Gill - Dr. Chris Boyd |
| Status: | Ongoing |
| City: | London (England) - Oxford (England) - Edinburgh (Scotland) |
| Project amount (€): | 162.670,02 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
SCooP (Supporting Children’s Physiotherapy for cystic fibrosis) Development of interventions to increase adherence to physiotherapy among young children with cystic fibrosis – Medical Research Council’s complex intervention framework phase I study. |
Psysiotherapy |
Clinical research | United Kingdom | Dr. Emma France |
| Status: | Ongoing |
| Institute: | University of Stirling |
| City: | Stirling (Scotland) |
| Project amount (€): | 22.800 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
The impact of spirometry reference equations on interpretation of longitudinal changes in lung function in individuals with CF: Analysis of UK CF Registry data |
Pulmonology |
Other | United Kingdom | Prof. Janet Stocks |
| Status: | Ongoing |
| City: | London (England) |
| Project amount (€): | 34.371 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Assessing Glycaemic Control in Individuals with Cystic Fibrosis Versus Healthy Controls: Validity and Feasibility of Different Methods |
Metabolic Complications of CF |
Clinical research | United Kingdom | Dr. Zoe Saynor |
| Status: | Ongoing |
| Institute: | University of Portsmouth |
| City: | Portsmouth (England) |
| Project amount (€): | 1.710 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Investigating Perfenidone-Induced Phototoxicity: A Critical Drug for Idiopathic Pulmonary Fibrosis |
Quality of care |
Clinical research | United Kingdom | Dr. Victoria McGuire |
| Status: | Ongoing |
| Institute: | University of Dundee |
| City: | Dundee (Scotland) |
| Project amount (€): | 1.710 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Portable Bladeless Fans and Infection Control in a Cystic Fibrosis Ward |
Nursing |
Clinical research | United Kingdom | Dr. Gordon MacGregor |
| Status: | Ongoing |
| Institute: | University of Glasgow |
| City: | Glasgow (Scotland) |
| Project amount (€): | 1.710 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Calprotectin is a potent chemoattractant for neutrophils and monocytes and contributes to unresolved inflammation in CF |
Immunology-Inflammation |
Basic research | United Kingdom | Dr. Robert Gray |
| Status: | Ongoing |
| Institute: | University of Edinburgh |
| City: | Edinburgh (Scotland) |
| Project amount (€): | 1.710 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
The Clinical Impact of Proton Pump Inhibitors on Antibiotic Efficacy in Cystic Fibrosis |
Antibiotics |
Clinical research | United Kingdom | Dr. Damian Downey |
| Status: | Ongoing |
| City: | Belfast (Northern Ireland) |
| Project amount (€): | 1.710 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Personalised Therapies for all: Restoring airway function in CF using Alternative Chloride Channels |
New Therapies Cell Biology |
Basic research | United Kingdom | Dr. Mike Gray |
| Status: | Ongoing |
| Institute: | University of Newcastle |
| City: | Newcastle (England) |
| Project amount (€): | 855.000 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
The Impact of Gut Dysbiosis on Lung Inflammation in Cystic Fibrosis |
Gastroenterology-Liver Immunology-Inflammation |
Basic research | United Kingdom | Dr. Daniel Peckham |
| Status: | Ongoing |
| Institute: | University of Leeds |
| City: | Leeds (England) |
| Project amount (€): | 855.000,6954 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Restoration of luminal fluidity and microbiota in the CF gut (CFGI-SRC) |
Gastroenterology-Liver Nutrition-Growth |
Basic research | United Kingdom | Prof. Soraya Shirazi-Beechey |
| Status: | Ongoing |
| Institute: | University of Liverpool |
| City: | Liverpool (England) |
| Project amount (€): | 854.651,16 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Novel Therapies for Mycobacterium abscessus |
New Therapies Antibiotics |
Basic research | United Kingdom | Prof. Andres Floto |
| Status: | Ongoing |
| Institute: | University of Cambridge |
| City: | Cambridge (England) |
| Project amount (€): | 854.932,7628 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Targeting joint disease in cystic fibrosis: identifying therapeutic targets in CF arthropathy |
Physiology Immunology-Inflammation |
Basic research | United Kingdom | Prof. Michael McDermott |
| Status: | Ongoing |
| Institute: | University of Leeds |
| City: | Leeds (England) |
| Project amount (€): | 423.394,86 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Physical Activity, Exercise, Sport and Recreation Promotion for Adolescents with CF |
Psysiotherapy Quality of care |
Clinical research | United Kingdom | Prof. Craig Williams |
| Status: | Ongoing |
| Institute: | University of Exeter |
| City: | Exeter (England) |
| Project amount (€): | 855.000 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
The Cystic Fibrosis Related Diabetes Strategic Research Centre (CFRD-SRC) |
Metabolic Complications of CF Cell Biology |
Basic research | United Kingdom | Prof. James Shaw |
| Status: | Ongoing |
| Institute: | University of Newcastle |
| City: | Newcastle (England) |
| Project amount (€): | 855.000 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Cystic Fibrosis Epidemiological Network (CF-EpiNet) – Harnessing Data to Improve Lives |
Quality of care Epidemiology |
Psychosocial | United Kingdom | Dr. Siobhan Carr |
| Status: | Ongoing |
| City: | London (England) |
| Project amount (€): | 851.875,26 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
INOVCF-Innovative non-CFTR Approaches for Cystic Fibrosis Therapy |
New Therapies Cell Biology |
Basic research | United Kingdom | Dr. Mike Gray |
| Status: | Ongoing |
| Institute: | University of Newcastle |
| City: | Newcastle (England) |
| Project amount (€): | 854.619,24 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Tackling Mycobacterium abscessus infection in Cystic Fibrosis |
New Therapies Microbiology |
Basic research | United Kingdom | Prof. Andres Floto |
| Status: | Ongoing |
| Institute: | University of Cambridge |
| City: | Cambridge (England) |
| Project amount (€): | 855.000 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Pseudomonal infection in CF: better detection, better understanding, better treatment |
New Therapies Microbiology |
Basic research | United Kingdom | Prof. Jane Davies |
| Status: | Ongoing |
| City: | London (England) |
| Project amount (€): | 850.107,12 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Personalised Medicine – Use of Advanced Analytics |
New Therapies Quality of care |
Basic research | United Kingdom | Prof. Mihaela van der Schaar |
| Status: | Ongoing |
| Institute: | University of Oxford |
| City: | Oxford (England) |
| Project amount (€): | 74.100 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Study of the effect of molecular drugs on the activity of CFTR protein on ex-vivo model of nasal epithelial cells in patients with cystic fibrosis and different genotypes. |
CFTR |
Basic research | Italy | Prof. Donatello Salvatore |
| Status: | Ongoing |
| City: | Potenza |
| Project amount (€): | 25.000 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Self-monitoring healthcare devices addressed to pre and post-transplant CF patients – Reconciliation |
Quality of care |
Clinical research | Italy | Dr.ssa Letizia Morlacchi & Dr.ssa Emilia Privitera |
| Status: | Ongoing |
| City: | Milan |
| Project amount (€): | 85.600 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Alternative strategies for F508del-CFTR repair: novel targets for drug discovery approach in cystic fibrosis |
New Therapies |
Basic research | Italy | Prof. Giorgio Cozza |
| Status: | Ongoing |
| City: | Milan |
| Project amount (€): | 200.000 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
The combined effect of cysteamine and epigallocatechin gallate in patients homozygous or heterozygous for F508del |
New Therapies |
Clinical research | Italy | Prof. Luigi Maiuri |
| Status: | Ongoing |
| City: | Milan |
| Project amount (€): | 29.830 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Defining research priorities in cystic fibrosis. Can existing knowledge and training in biomedical research affect the choice? |
Other Issues |
Psychosocial | Italy | Prof. Roberto Buzzetti |
| Status: | Ongoing |
| Researcher: | Luigi Graziano |
| City: | Bergamo |
| Project amount (€): | 2.000 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Computer assisted diagnosis (CAD) for monitoring CF airway disease (CAD) – The CAD-CAD project |
Pulmonology Physiology |
Clinical research | Netherlands | Prof. Harm Tiddens |
| Start date: | 2017 |
| End date: | 2021 |
| Website URL: | Click here to visit website |
| Status: | Ongoing |
| Institute: | Erasmus MC |
| City: | Rotterdam |
| Project amount (€): | 100.000 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Theratyping of disease causing variants in CF |
Cell Biology New Therapies |
Basic research | Netherlands | Prof. Ineke Braakman |
| Start date: | 2017 |
| End date: | 2021 |
| Website URL: | Click here to visit website |
| Status: | Ongoing |
| Researcher: | Dr. Bertrand Kleizen |
| Institute: | Universiteit Utrecht |
| City: | Utrecht |
| Project amount (€): | 100.000 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Analyzing the exact defect in the construction of the chloride channel in various CF mutations |
Cell Biology CFTR |
Basic research | Netherlands | Prof. Ineke Braakman |
| Start date: | 2017 |
| End date: | 2021 |
| Website URL: | Click here to visit website |
| Status: | Ongoing |
| Researcher: | Dr. Bertrand Kleizen |
| Institute: | Universiteit Utrecht |
| City: | Utrecht |
| Project amount (€): | 50.000 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Mechanism of action of new correctors of the F508del mutation |
CFTR New Therapies |
Basic research | Netherlands | Prof. Jeffrey Beekman |
| Start date: | 2017 |
| End date: | 2021 |
| Website URL: | Click here to visit website |
| Status: | Ongoing |
| Researcher: | Dr. Marne Hagemeier |
| Institute: | UMC Utrecht |
| City: | Utrecht |
| Project amount (€): | 150.000 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Studying similarities and differences between mini-guts, mini-lungs and mini-noses |
CFTR Cell Biology |
Basic research | Netherlands | Prof. Jeffrey Beekman |
| Start date: | 2017 |
| End date: | 2021 |
| Website URL: | Click here to visit website |
| Status: | Ongoing |
| Researcher: | Dr. Gimano Amatngalim |
| Institute: | UMC Utrecht |
| City: | Utrecht |
| Project amount (€): | 25.000 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Bicarbonate transport in human intestinal biopsies and organoids (CF/nonCF) |
Cell Biology Physiology |
Basic research | Netherlands | Prof. Hugo de Jonge |
| Start date: | 2017 |
| End date: | 2021 |
| Website URL: | Click here to visit website |
| Status: | Ongoing |
| Researcher: | Dr. Marcel Bijvelds |
| Institute: | Erasmus MC |
| City: | Rotterdam |
| Project amount (€): | 50.000 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Identifying genetic modifiers of CFTR expression and function in primary cell cultures of people with cystic fibrosis |
CFTR Genetics |
Basic research | Netherlands | Prof. Kors van der Ent |
| Start date: | 2017 |
| End date: | 2021 |
| Website URL: | Click here to visit website |
| Status: | Ongoing |
| Researcher: | Dr. Marne Hagemeier |
| Institute: | UMC Utrecht |
| City: | Utrecht |
| Project amount (€): | 167.000 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Standardisation of organoid responses |
CFTR Cell Biology |
Basic research | Netherlands | Prof. Jeffrey Beekman |
| Start date: | 2017 |
| End date: | 2021 |
| Website URL: | Click here to visit website |
| Status: | Ongoing |
| Researcher: | Dr. Marne Hagemeier |
| Institute: | UMC Utrecht |
| City: | Utrecht |
| Project amount (€): | 25.000 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
SAPPHIRE study: A national validation study of an intestinal stem cell model to predict and to improve the long-term efficacy of CFTR modulating therapy in individual subjects with CF |
CFTR New Therapies |
Clinical research | Netherlands | Prof. Kors van der Ent - Prof. Jeffrey Beekman |
| Start date: | 2017 |
| End date: | 2021 |
| Website URL: | Click here to visit website |
| Status: | Ongoing |
| Researcher: | Dr. Marne Hagemeier |
| Institute: | UMC Utrecht |
| City: | Utrecht |
| Project amount (€): | 100.000 |
| Project name: | Project category: | Kind of research: | Country: | Principle investigator: |
|---|---|---|---|---|
Understanding of dose-effect relationships of CFTR modulators in individual patients with Cystic Fibrosis to realise a personalised dosing regimen per patient |
New Therapies CFTR |
Clinical research | Netherlands | Prof. Kors van der Ent |
| Start date: | 2017 |
| End date: | 2021 |
| Website URL: | Click here to visit website |
| Status: | Ongoing |
| Researcher: | Dr. Marne Hagemeier |
| Institute: | UMC Utrecht |
| City: | Utrecht |
| Project amount (€): | 240.000 |
Contact information
- Hilde De Keyser
- hilde.dekeyser@cf-europe.eu
- 0032 - (0)2 61 32 716