A type of CFTR modulator medicine that helps to keep faulty CFTR doorways open.

Some CFTR gene mutations mean that CFTR protein doorways at the cell surface don’t let chloride pass through the doorway. Gating mutations are an example. Potentiators help to keep faulty CFTR doorways open, so that more chloride can flow through the doorways.

Ivacaftor is an example of a potentiator. Potentiators can be used with other CFTR modulators such as correctors.

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