A type of CFTR modulator that increases how many CFTR doorway proteins a cell makes.
Some CFTR gene mutations mean fewer CFTR doorway proteins are made by cells. Amplifiers increase how many CFTR doorway proteins are made. More CFTR doorways means more chloride can pass through at the cell surface.
No amplifiers are licenced for use yet. Amplifiers could be used with other CFTR modulators like potentiators and correctors.